副研究員
黃曉蓓，中國科學院重慶綠色智能技術研究院，副研究員，重慶市科技特派專家，，工學博士。2017年博士畢業(yè)于四川大學生物醫(yī)學工程專業(yè)。愛爾蘭都柏林大學公派聯(lián)合培養(yǎng)博士，澳門大學博士后。2024入選重慶市青年創(chuàng)新人才。
主要研究方向為開發(fā)可用于生物醫(yī)藥領域的新型仿生高分子材料。目前以第一作者（共一）或通訊作者（共通）在一區(qū)雜志Journal of Controlled Release、Acta Biomaterialia、ACS Macro Letters、Chemical Communications等頂級期刊發(fā)表學術論文20余篇，其中IF>10的6篇，高被引1篇。主持國家自然科學基金、重慶市自然科學基金等科研項目10余項。申請國家發(fā)明專利3項，獲批2項。《Supramolecular Materials》青年編委。
干細胞與衰老研究中心
生物醫(yī)用高分子，藥物遞送，基因遞送
2022年 院優(yōu)秀特別助理研究員
2023年 院優(yōu)秀員工
2024年 院優(yōu)秀員工
1. Xiaobei Huang a,*, Ning Mu b,1, Yuanfu Ding d,1, Rong Huang a, Wei Wu e,*, Li Li a,*, Tunan Chen b,c,*. Tumor microenvironment targeting for glioblastoma multiforme treatment via hybrid cell membrane coating supramolecular micelles. Journal of Controlled Release. 2024 , 336, 194-203.?
2. Yongguo Xiang#, Zhu Qiu#, Yuanfu Ding, Miaomiao Du, Ning Gao, Huijie Cao, Hangjia Zuo, Hong Cheng, Xiang Gao, Shijie Zheng, Wenjuan Wan, Xiaobei Huang*, Ke Hu*. Dexamethasone-loaded ROS Stimuli-responsive Nanogels for Topical Ocular Therapy of Corneal Neovascularization. Journal of Controlled Release. 2024, 372, 874-884.
3. Li Zhu, Yuan Zhong, Meng Yan, Sheng Ni, Xiong Zhao, Shuai Wu, Guixue Wang,Kai Qu, Kun Zhang, Qingjia Chi, Xian Qin,* Chuanwei Li,* Xiaobei Huang,* Wei Wu,*, Macrophage Membrane-Encapsulated Dopamine-Modified Poly Cyclodextrin Multifunctional Biomimetic Nanoparticles for Atherosclerosis Therapy. ACS Applied Materials & Interfaces. 2024, 16, 25, 32027-32044.
4. Shengyun Hu?, Kunkun Xia?, Xiaobei Huang?, Ye Zhao, Qingqing Zhang, Dongdong Huang, Weiyi Xu, Zhengju Chen*, Chenfei Wang* and Zhiyong Zhang*, Multifunctional CaCO3@Cur@QTX125@HA nanoparticles for efectively inhibiting growth of colorectal cancer cells. Journal of Nanobiotechnology. 2023, 21:353.
5. Jiahao Shi, Bin Ma, Yuhe Zhang, Haiyang Yong, Zhili Li, Sigen A*, Xiaobei Huang*, and Dezhong Zhou*. Targeted Delivery of Anticancer Therapeutics with Polymers by Harnessing Tumor Microenvironment Acidity. Chemistry of Materials. 2023, 35 (17), 6573-6590.
6. Xiaobei Huang, Ning Mu, Yuanfu Ding, Hou Wang Lam, Ludan Yue, Cheng Gao, Tunan Chen,* ZhenYuan* and Ruibing Wang*, Targeted delivery and enhanced uptake of chemo-photodynamic nanomedicine for melanoma treatment. Acta Biomaterialia. 2022, 147, 356-365.
7. Xiaobei Huang,? Tunan Chen,? Ning Mu, Hou Wang Lam, Chen Sun, Ludan Yue, Qian Cheng, Cheng Gao, Zhen Yuan* and Ruibing Wang*, Supramolecular micelles as multifunctional theranostic agents for synergistic photodynamic therapy and hypoxia-activated chemotherapy. Acta? Biomaterialia. 2021, 131, 483-492.?
8. Chenfei Wang,? Xiaobei Huang,? Litao Sun, Qiuxia Li, ZhiliLi, Haiyang Yong, Delu Che, Cong Yan, Songmei Geng,*Wenxin Wang and Dezhong Zhou*, Cyclic poly(?-amino ester)s with enhanced gene transfection activity synthesized through intra-molecular cyclization. Chemical Communications. 2022, DOI: 10.1039/d1cc06480k.?
9. Qiuxia Li,? Litao Sun,? Xiaobei Huang,? Shuai Liu,* Haiyang Yong, Chenfei Wang, Jianzhong Li,* and Dezhong Zhou*, Genetic Engineering of Adipose-Derived Stem Cells Using Biodegradable and Lipid-Like Highly Branched Poly(β-amino ester)s. ACS Macro Letters. 2022, 11, 636-642.
10. Haiyang Yong,# Zhili Li,# Xiaobei Huang,# Kaixuan Wang, Ya-Nan Zhou, Qiuxia Li, Jianjun Shi,* Ming Liu, Dezhong Zhou.*, Superhydrophobic Materials: Versatility and Translational Applications. Advanced materials interfaces. 2022, 2200435.?
1、國自然青年科學基金項目，《仿生“雙鎖”超分子組裝體抗腦膠質(zhì)瘤的效應研究》，2025-2027，
5240031367，30萬，主持。?
2、新重慶青年創(chuàng)新人才項目，《仿生超分子組裝體抗腦膠質(zhì)瘤的效應研究》，2025-2027，2024NSCQ-qncxX0306，60萬，主持。
3、國家生豬創(chuàng)新中心先導科技項目，《永生化細胞系構建》，2022-2024，NCTIP-XD/B1332000576，60萬，主持。
4、重慶市自然科學基金面上項目，《基于多形性膠質(zhì)母細胞瘤的雜化細胞膜包覆納米藥物的同源靶向遞送機制及個性化治療研究》，2023-2025，CSTB2023NSCQ-MSX1077，5萬，主持。
5、中國科學院重慶綠色智能技術研究院基礎研究課題，《仿生超分子組裝體抗腫瘤的效應研究》，2024-2026，25萬，主持。
6、重慶榮昌農(nóng)牧高新技術產(chǎn)業(yè)研發(fā)專項，《表達人抗體基因工程豬的培育》，2020-2023，cstc2020ngzx0001，40萬，主持。
7、重慶市留創(chuàng)計劃，5萬，主持。
中國科學院重慶綠色智能技術研究院 版權所有京ICP備05002857號渝公網(wǎng)安備50010943035號
