
副研究員
陳蕭寒博士,中國(guó)科學(xué)院重慶綠色智能技術(shù)研究院副研究員。2012年本科畢業(yè)于華中師范大學(xué)化學(xué)學(xué)院,2018年于美國(guó)伊利諾伊理工大學(xué)化學(xué)學(xué)院獲得博士學(xué)位。2018年~2020年,在美國(guó)伊利諾伊理工大學(xué)繼續(xù)從事博士后研究。2022年~至今,中科院重慶綠色智能技術(shù)研究院。研究主要涉及蛋白質(zhì)納米孔和固體納米孔的單分子檢測(cè)技術(shù)在疾病檢測(cè)、預(yù)后診斷、環(huán)境監(jiān)測(cè)的開(kāi)發(fā)與應(yīng)用,對(duì)單分子核酸以及蛋白質(zhì)的生物信息識(shí)別具有重要意義。至今已在國(guó)際知名期刊上發(fā)表了19篇學(xué)術(shù)論文,比如:Small Methods、Biosensors & Bioeletronics、ACS Applied Materials and Interfaces、Nanoscale、Analytical Chemistry等(論文引用253次,H-index為10),并先后14次參加國(guó)際會(huì)議進(jìn)行口頭報(bào)告、海報(bào)、論文。
精準(zhǔn)醫(yī)療單分子診斷技術(shù)研究中心
單分子檢測(cè)技術(shù)及應(yīng)用、生物探針研發(fā)
1.Nanopore Stochastic Sensing based on Non-covalent Interactions. Anal. Chem. 2021,第一作者;
2.Simultaneous Detection of Multiple Proteases using a Non-array Nanopore Platform. Nanoscale. 2021, 第一作者;
3.Nanopore Detection of Metal Ions: Current Status and Future Directions. Small Methods, 2020,共同一作;
4.Salt-Mediated Nanopore Detection of ADAM-17, ACS Appl. Bio Mater., 2019,第一作者;
5.Nanopore Label-Free Detection of Single-nucleotide Detection in Bax/Bax 2. Electrophoresis, 2018,第一作者;
6.Label-Free Detection of DNA Mutations by Nanopore Analysis, ACS Appl. Mater. Interfaces. 2018,第一作者;
7.Nanoparticle-assisted detection of nucleic acids in a polymeric nanopore with a large pore size. Biosensors and Bioelectronics, 2022. 第二作者;
8.Chemically Functionalized Conical PET Nanopore for Protein Detection at the Single-molecule Level. Biosensors and Bioelectronics, 2020,第二作者;
9.Joint entropy-assisted Graphene Oxide-based Biosensing Platform for Simultaneous Detection of Multiplex MMPs/ADAMs. Anal. Chem., 2020,第二作者;
10.Rapid and Sensitive Detection of the Activity of ADAM17 using Graphene Oxide-based Fluorescent Sensor. Analyst,2019,第二作者。